I think we can all agree there would be a massive drop in profits for the company if Satou disappeared.
My vague impression from the LNs is that at this point the company would still be at least break-even if they continued to sell the products that are now produced using materials from the labyrinth and other non-Satou materials. And end to the good times, but not disaster.
No new mining or farming villages, only a trickle of new products without Satou to whip up manufacturing tools and aids, and the company would lose almost all of its influence with both Nanashi and Kuro gone. They might also gradually lose product lines where they depend on tools and equipment from Satou that they can't duplicate.